Perspective of Additive Manufacturing Selective Laser Melting in Co-Cr-Mo Alloy in the Consolidation of Dental Prosthesis

This chapter seeks to compare the properties of samples manufactured by additive manufacturing (AM) by the selective laser melting (SLM) technology and compare with the precision casting (PC) processes using the Co-Cr-Mo (ASTM F75) alloy to manufacture of dental prosthesis. This AM process can be manufactured three-dimensional models by means of a laser beam that completely melts particles of powder deposited layer by layer. However, it is still relevant to know the properties of: performance, dimensional, mechanical and microstructural of this laser melting process and compare with a convencional process. The results of mechanical evaluation showed that the SLM technique provides superior mechanical properties compared to those obtained by the PC technique. It is possible to verify that the consolidation by SLM technique results in lower presence of porosity than PC technique. In addition, PC samples presented a gross dendritic microstructure of casting process. Microstructural analysis of SLM samples results in a characteristic morphology of layer manufacturing with ultrafine grains and a high chemical homogeneity. In this way, the development of the present study evidenced to improve the manufacture of customized components (copings) using the SLM technology

Predictors of Survival After Head and Neck Squamous Cell Carcinoma in South America: The InterCHANGE Study.

PURPOSE: Head and neck squamous cell carcinoma (HNSCC) incidence is high in South America, where recent data on survival are sparse. We investigated the main predictors of HNSCC survival in Brazil, Argentina, Uruguay, and Colombia. METHODS: Sociodemographic and lifestyle information was obtained from standardized interviews, and clinicopathologic data were extracted from medical records and pathologic reports. The Kaplan-Meier method and Cox regression were used for statistical analyses. RESULTS: Of 1,463 patients, 378 had a larynx cancer (LC), 78 hypopharynx cancer (HC), 599 oral cavity cancer (OC), and 408 oropharynx cancer (OPC). Most patients (55.5%) were diagnosed with stage IV disease, ranging from 47.6% for LC to 70.8% for OPC. Three-year survival rates were 56.0% for LC, 54.7% for OC, 48.0% for OPC, and 37.8% for HC. In multivariable models, patients with stage IV disease had approximately 7.6 (LC/HC), 11.7 (OC), and 3.5 (OPC) times higher mortality than patients with stage I disease. Current and former drinkers with LC or HC had approximately 2 times higher mortality than never-drinkers. In addition, older age at diagnosis was independently associated with worse survival for all sites. In a subset analysis of 198 patients with OPC with available human papillomavirus (HPV) type 16 data, those with HPV-unrelated OPC had a significantly worse 3-year survival compared with those with HPV-related OPC (44.6% v 75.6%, respectively), corresponding to a 3.4 times higher mortality. CONCLUSION: Late stage at diagnosis was the strongest predictor of lower HNSCC survival. Early cancer detection and reduction of harmful alcohol use are fundamental to decrease the high burden of HNSCC in South America

First gravitational-wave burst GW150914: MASTER optical follow-up observations

The Advanced LIGO observatory recently reported the first direct detection of the gravitational waves (GWs) predicted by Einstein & Sitzungsber. We report on the first optical observations of the GW source GW150914 error region with the Global MASTER Robotic Net. Between the optical telescopes of electromagnetic support, the covered area is dominated by MASTER with an unfiltered magnitude up to 19.9 mag (5σ). We detected several optical transients, which proved to be unconnected with the GW event. The main input to investigate the final error box of GW150914 was made by the MASTER-SAAO robotic telescope, which covered 70 per cent of the final GW error box and 90 per cent of the common localization area of the LIGO and Fermi events. Our result is consistent with the conclusion (Abbott et al. 2016a) that GWs from GW150914 were produced in a binary black hole merger. At the same time, we cannot exclude that MASTER OT J040938.68-541316.9 exploded on 2015 September 14.Fil: Lipunov, V. M.. Lomonosov Moscow State University; RusiaFil: Kornilov, V.. Lomonosov Moscow State University; RusiaFil: Gorbovskoy, E.. Lomonosov Moscow State University; RusiaFil: Buckley, D. A. H.. South African Astronomical Observatory; SudáfricaFil: Tiurina, N.. Lomonosov Moscow State University; RusiaFil: Balanutsa, P.. Lomonosov Moscow State University; RusiaFil: Kuznetsov, A.. Lomonosov Moscow State University; RusiaFil: Greiner, J.. Max-Planck-Institut für extraterrestrische Physik; AlemaniaFil: Vladimirov, V.. Lomonosov Moscow State University; RusiaFil: Vlasenko, D.. Lomonosov Moscow State University; RusiaFil: Chazov, V.. Lomonosov Moscow State University; RusiaFil: Kuvshinov, D.. Lomonosov Moscow State University; RusiaFil: Gabovich, A.. Blagoveschensk State Pedagogical University; RusiaFil: Potter, S. B.. South African Astronomical Observatory; SudáfricaFil: Kniazev, A.. South African Astronomical Observatory; SudáfricaFil: Crawford, S.. South African Astronomical Observatory;Fil: Rebolo Lopez, R.. Instituto de Astrofacuteisica de Canarias Vía Láctea; EspañaFil: Serra Ricart, M.. Instituto de Astrofacuteisica de Canarias Vía Láctea; EspañaFil: Israelian, G.. Instituto de Astrofacuteisica de Canarias Vía Láctea; EspañaFil: Lodieu, N.. Instituto de Astrofacuteisica de Canarias Vía Láctea; EspañaFil: Gress, O.. Irkutsk State University; RusiaFil: Budnev, N.. Irkutsk State University; RusiaFil: Ivanov, K.. Irkutsk State University; RusiaFil: Poleschuk, V.. Irkutsk State University; RusiaFil: Yazev, S.. Irkutsk State University; RusiaFil: Tlatov, A.. Russian Academy of Sciences. Pulkovo Astronomical Observatory; RusiaFil: Senik, V.. Russian Academy of Sciences. Pulkovo Astronomical Observatory; RusiaFil: Yurkov, V.. Blagoveschensk State Pedagogical University; RusiaFil: Dormidontov, D.. Russian Academy of Sciences. Pulkovo Astronomical Observatory; RusiaFil: Parkhomenko, A.. Russian Academy of Sciences. Pulkovo Astronomical Observatory; RusiaFil: Sergienko, Yu.. Blagoveschensk State Pedagogical University; RusiaFil: Podestá, Ricardo César. Universidad Nacional de San Juan. Facultad de Ciencias Exactas Físicas y Naturales. Departamento de Informática. Observatorio Astronómico Félix Aguilar; ArgentinaFil: Levato, Orlando Hugo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio. Universidad Nacional de San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio; ArgentinaFil: López, Carlos Eduardo. Universidad Nacional de San Juan. Facultad de Ciencias Exactas Físicas y Naturales. Departamento de Informática. Observatorio Astronómico Félix Aguilar; ArgentinaFil: Saffe, Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio. Universidad Nacional de San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio; ArgentinaFil: Podestá, Florencia. Universidad Nacional de San Juan. Facultad de Ciencias Exactas Físicas y Naturales. Departamento de Informática. Observatorio Astronómico Félix Aguilar; ArgentinaFil: Mallamaci, Claudio Carlos. Universidad Nacional de San Juan. Facultad de Ciencias Exactas Físicas y Naturales. Departamento de Informática. Observatorio Astronómico Félix Aguilar; Argentin